Re20 Fine

Rebuild Your Under-Eyes. Don't Just Fill Them.

Restores the eye area's own support —
naturally rested eyes even when you smile.
No swelling. No blue Tyndall tint. No bulge.

Under-eye filler at Ozhean Zoey
softens bags and dark circles by up to 90% —in a single visit, without surgery.

Book An Appointment

Medical Precision, Refined
Body Shaping

Non-surgical Approach
Fat Reduction

Featuring Cooltech Define

BOOK AN APPOINTMENT

50µm
Ultra-Fine Particles,
Refined For The Eye Area

50µm
Ultra-Fine
Particles, Refined
For The Eye Area

hADM
Made From Real Human Skin Matrix

hADM
Made From Real
Human
Skin Matrix

3 Layers
Rebuilds Structure, Not Just Surface Hydration

3 Layers
Rebuilds Structure,
Not Just Surface
Hydration

눈 밑부터 다시 세우는 아름다움

Re20 Fine in Singapore

The under-eye is the first place tiredness shows — and the hardest to treat well. The skin around your eyes is the thinnest on your face, and it never stops moving.

That's exactly why ordinary skin boosters and standard fillers so often disappoint here — the particles are too coarse, the product swells, or it bulges when you smile.

Re20 Fine was engineered specifically for this delicate zone, available now in Singapore.

눈 밑 구조를 다시 세우다

What Is Re20 Fine?

More than a booster.
A foundation for your under-eyes.

Re20 Fine is made from human acellular dermal matrix (hADM): real skin scaffold — collagen, elastin and other matrix proteins — with the cells removed. It replenishes the framework your skin is built on, rather than simply adding water or volume.

Book An Appointment

Why Choose Re20 Fine?

Refined to 50µm for the eyes

The particles are micronised to roughly 50µm — small enough to settle smoothly into paper-thin under-eye skin. That means less resistance on injection, less swelling, and bumps that settle faster than coarser boosters.

Natural, from within

Because it integrates with your own tissue and rebuilds structure over time, the result reads as your skin looking rested — not as "work done."
No overfilled look, no shine, no giveaway.

The Science Behind Re20 Fine

The Science
Behind Re20 Fine

Young skin isn't about the cells. It's about the house they live in.

Every skin cell sits inside an invisible scaffold called the extracellular matrix — the ECM.

Major regenerative research now treats the ECM not as passive packing material, but as a living "longevity organ" that decides how your skin ages.

The Soil, Not the Plant

ECM is the foundation of youth

Think of your skin as a garden. Fillers water the plants. But if the soil itself is depleted, no amount of watering helps for long. The ECM is that soil — and when it collapses, firmness, elasticity, wound healing and even cell renewal decline together.

A Paradigm Shift

Reconstruct the environment

The old approach tried to treat the cell. The current approach rebuilds the environment the cell depends on. Restore the scaffold, and the skin's own repair machinery restarts — this is why researchers describe ECM restoration as structural medicine, not cosmetic touch-up.

Measurable Renewal

Improvement across the board

In human application testing, Re20 was documented to improve multiple structural and functional skin measures at once — density, elasticity, barrier strength, hydration and fine-line depth among them — with effects continuing to build over 20 weeks. 

Skin-quality measures and study figures referenced from published human application data (Int. J. Mol. Sci. 2026;27:2193) alongside our clinical observation. Individual results vary; a consultation is required to assess suitability.

How Does Re20 Fine Work?

How Does
Re20 Fine Work?

One material. Three ways it renews your skin.

One material.
Three ways it renews your skin.

Re20 Fine doesn't just sit under the skin. Its ECM material works through three complementary mechanisms — tap each layer to see how.

Scaffold

A structural template your own cells can move into and rebuild upon. It physically restores the framework that thin under-eye skin has lost.

Signal

The matrix acts as a biochemical communicator, prompting resident fibroblasts to switch back on and produce fresh collagen and elastin.

Mechanotransduction

Restored structure lets skin translate physical movement into healthy biological response again — the way youthful, resilient skin does.

Remodelling, Not Reaction

Because Re20 Fine is derived from real human skin matrix, your body recognises it. It's gradually integrated through a natural, host-mediated pathway — the cells removed during processing mean minimal immune response, and no foreign-body reaction of the kind associated with some synthetic stimulators. Clinical data on the material reports no plug formation and no chronic nodules — the scaffold is progressively remodelled into your own functional tissue.

Book An Appointment

Re20 Fine vs Standard HA Fillers

	Standard HA Filler	Re20 Fine
Material Behaviour	Draws water in — swelling can worsen the day after	Human-derived matrix your body recognises and integrates
Stability	Can migrate in a high-movement zone, creating irregular bumps	Rebuilds the scaffold — correction is held in place, not floating
Smile Movement	Visible bulge may appear when you smile	Moves with your face; smile-bulge is dramatically reduced
Thin Skin Appearance	Risk of a bluish Tyndall tint through thin skin	Injected at appropriate depth, Tyndall tint is not typically seen
Skin Quality	Adds volume, but does not improve skin quality	Thickens and improves the quality of the skin itself over time

Re20 Fine becomes part of your skin — not a deposit sitting under it.

This is the difference patients feel most. Standard hyaluronic acid (HA) fillers are hydrophilic — they pull water in. In a constantly-moving zone like the under-eye, that can mean swelling that worsens the next day, migration, a bluish Tyndall tint, and a bulge that appears when you smile. Re20 Fine behaves differently.

Re20 Fine vs Re20

A version built for the eyes, but the same science.

You may already know Re20 — our ECM skin booster for the full face and neck. Re20 Fine is its precision sibling: the same human-derived matrix, refined specifically for the most delicate skin on your face.

	Re20	Re20 Fine
Positioning	Original ECM skin booster	Refined for the eyes
Particle Size	75µm	50µm — ultra-fine
Ideal For	Full face, neck	Under-eyes, thin skin, lips
Targets	Density, tone, pores	Hollows, dark circles, fine lines
Role	Overall skin foundation	Precision, delicate-area renewal

Why Fine Is the Right Choice for Under-Eyes

Under-eye skin can be less than half a millimetre thick. Coarser particles risk visible bumps, prolonged embossing and easy bruising here. By micronising the same matrix to ~50µm, Re20 Fine passes through delicate tissue with less resistance — meaning a smoother settle, less swelling, faster recovery, and the precision needed to correct hollows and dark circles without looking overfilled.

For the eyes specifically, Fine is simply the safer, more refined tool.

What Conditions & Areas Can Re20 Fine Treat?

Designed for the eyes. Effective on every tired-eye concern.

Dark circles

Dark Eye Rings

Softens hollowing and, as skin quality improves and circulation supports a healthier tone, helps lighten the tired shadow that makes you look worn out even when rested.

Hollows

Sunken Tear Troughs

Restores gentle, natural volume from within the tissue — smoothing the hollow beneath the lash line without the heaviness of over-filling.

Fine lines

Crêpey, Fragile Skin

Rebuilds dermal thickness so fine lines, translucency and that delicate "crêpe-paper" texture are visibly refined.

Elasticity

Loss of Firmness

As the matrix prompts new collagen and elastin, the under-eye regains firmness and bounce it had lost.

Pigmentation

Periocular Discolouration

Improves the skin's internal environment, supporting a brighter, more even tone in the peri-eye area over the following weeks.

Prevention

Early Ageing

For those who want to strengthen the eye area before deep lines set in — a foundation treatment that keeps skin resilient.

Beyond the Eyes

Just as at home on lips and smile lines.

The lips and the skin framing them are thin, mobile and quick to show age — the same brief Re20 Fine was built for. Here, its fine matrix rebuilds structure and hydration from within, rather than parking a bolus of gel on top.

Freshens & Hydrates

Replenishes the lip's own matrix for a naturally fuller, healthier, hydrated surface — the "quiet" plump that comes from within, not from overfilling.

Natural, Subtle Augmentation

Restores gentle volume and definition to the vermillion and lip body without the stiff, "done" look of heavy HA lip filler. It moves as your lips move.

Softens Smile &
Lip Lines

Rebuilds thinning skin along the "barcode" lip lines and the smile lines framing the mouth — refining texture and softening the creases that deepen with age.

The Ideal Combination

Our Signature Under-eye Protocol

REBUILD

Re20 Fine

VOLUME

PEG-HA Filler

our Protocol

Re20 Fine rebuilds the foundation. Pair it with a low-swelling PEG-HA filler for immediate, precise volume correction, and you have RE-NEAU™ — Dr Park Ji-Youn's proprietary under-eye protocol.

The PEG-HA delivers early structural correction with minimal swelling; Re20 Fine rebuilds the scaffold and improves tone so results look natural and hold longer. For deeper dark circles and fragile skin, RE-NEAU-EST™ adds a brightening polynucleotide layer.

Explore RE-NEAU Under-eye Protocol

What Are The Benefits of Re20 Fine?

No Bulge
When You Smile

No Bulge When You Smile

Because it integrates with tissue and moves with your face, the smile-bulge patients dread with standard filler is dramatically reduced.

Minimal Swelling

Fine particles and a matrix that doesn't pull in water mean far less puffiness — no anxious "wait for it to settle" period.

Rebuilds,
Doesn't Just Fill

Rebuilds, Doesn't Just Fill

You're improving the quality and thickness of the skin itself — an effect that keeps developing as your own collagen returns.

Naturally Recognised

Human-derived ECM with strong biocompatibility — no BDDE crosslinker, gradually and naturally remodelled by your body.

Precision for Delicate Skin

Purpose-refined at 50µm for the thinnest facial skin — smoother settle, faster recovery, less bruising.

Minimal Downtime

Most patients return to daily life the same day, with any minor marks settling within 24–72 hours.

Re20 Fine vs Conventional Under-Eye Options

	Standard HA Filler	PN / collagen booster	Re20 Fine
Swelling after treatment	Common — can worsen next day	Mild	Minimal — fine, non-hydrophilic
Bulge when smiling	Often visible	Improved	Dramatically reduced
Tyndall (blue) risk	Possible	Low	Not typical at correct depth
Rebuilds skin structure	No — volume only	Partial (stimulates)	Yes — replenishes ECM directly
Improves skin quality & tone	No	Some	Yes — density, firmness, tone
Material	Synthetic HA gel	DNA fragments / collagen	Real human-derived matrix (hADM)
Refined for delicate eye skin	Not specifically	Varies	Yes — 50µm ultra-fine

What to Expect
From Re20 Fine Treatment?

What to Expect From Re20 Fine Treatment?

Re20 Fine is a rebuilding treatment, not an overnight fix.
That's the point: results emerge as your skin integrates the matrix and produces its own collagen,
so they read as natural and hold well.

Re20 Fine is a rebuilding treatment, not an overnight fix. That's the point: results emerge as your skin integrates the matrix and produces its own collagen, so they read as natural and hold well.

Day 1–3

Immediately After

A subtle refreshed look. Mild redness or tiny injection points may show briefly and are normal.

Week 2–4

Early Improvement

Texture begins to refine; fine lines soften and hydration improves as the skin settles.

Week 6–12

Progressive Results

Firmness and brightness increase; dark circles continue to improve as fresh collagen builds.

Ongoing

Full Results

Skin appears firmer, smoother and more rested. A course is often recommended, with maintenance to sustain results.

Day 1–3

Immediately After

A subtle refreshed look. Mild redness or tiny injection points may show briefly and are normal.

Week 2–4

Early Improvement

Texture begins to refine; fine lines soften and hydration improves as the skin settles.

Week 6–12

Progressive Results

Firmness and brightness increase; dark circles continue to improve as fresh collagen builds.

Ongoing

Full Results

Skin appears firmer, smoother and more rested. A course is often recommended, with maintenance to sustain results.

Your doctor will advise on the ideal number of sessions and spacing for your skin. Downtime is minimal; avoid strenuous exercise, saunas and alcohol for 24–48 hours. Individual results and timelines vary.

The Ozhean Zoey Difference

Global Presence

10 Clinics Worldwide: With 7 clinics across South Korea, 2 in Malaysia, and 1 in Singapore, we deliver consistent, high-quality aesthetic care throughout Asia.

Expert Leadership

Dr. Ji-Youn Park, Founder & Medical Director: A Korean board-certified dermatologist, Dr. Park has authored over 30 scientific papers and developed the SKIN FIT program, helping over 20,000 patients achieve radiant skin.
Member, Global Aesthetic Leaders Club for Ultherapy Prime.

Medical Expertise

Over 20 Years of Experience: Our dedicated team of board-certified dermatologists and experienced medical professionals ensures expert care as well as clinically proven and trusted results.
Team of 20+ Skin Specialists: Led by experienced dermatologist Dr. Park Ji-Youn, our extensive team spans across Asia.

Industry Recognition

Merz Aesthetics Gold Award (2023-2024), Infinite Award (2025) for Ultherapy
Elogio Asia Top User Award for Juvelook
Star Player Award for PB Serum (Celluject)
10Therma Prestige Partner Award
TEOXANE Teosyal Beauty Booster Award Singapore

Proven Patient Satisfaction

Trusted by 10,000+ Patients: Proven results, with a rapidly growing patient base.
High Return Rate: More than 80% of our clients return for additional treatments, a testament to their trust and satisfaction.

Personalised & Innovative Care

Customised Treatment Plans: Each procedure is meticulously tailored to individual skin conditions and personal goals, ensuring natural-looking and effective results.
AI Imaging & Analysis: Personalised care plans created using AI skin imaging technology.

Our Doctors

Dr. Park Ji-Youn

Group Medical Director

A Korean board-certified dermatologist and founder of the Ozhean Skin and Plastic Surgery Network, she has authored over 30 scientific papers and created the SKIN FIT program, which has helped over 20,000 patients achieve radiant, healthy skin. She believes in personalised, evidence-based treatments that enhance natural beauty and is proud to bring the Ozhean philosophy to Singapore.

Dr. Kenneth Long

Senior Aesthetic Physician

A seasoned aesthetic physician with a strong surgical foundation, he has over 15 years of medical experience spanning multiple subspecialties. Trained under the National Healthcare Group and holding postgraduate surgical qualifications, his practice is grounded in precision, anatomical accuracy, and safety. He focuses on facial harmony, structural refinement, and collagen-based regenerative treatments, with a philosophy centred on thoughtful decision-making, conservative execution, and long-term, natural ageing.

Dr. Dexter Sia

Resident Aesthetic Physician

A dedicated physician with a background in family medicine, ENT, anaesthesia, dermatology, and aesthetic medicine. With experience in clinical dermatology, facial reconstruction, and collagen-based treatments, he focuses on anti-aging and long-term skin health. He believes in personalised and holistic care, combining medical expertise with artistic sensibility to support each patient’s confidence and well-being.

Dr. Tan Jun Yang

Resident Aesthetic Physician

Dr. Tan Jun Yang is an aesthetic physician with a clinical background spanning Cardiothoracic Surgery, Anaesthesia, General Surgery, and Dermatology. His time at the National Heart Centre Singapore and the National University Hospital Heart Centre gave him extensive surgical training in complex heart and lung conditions as well as post-operative reconstructive procedures, a depth of experience that allows him to deliver results with confidence, consistency, and the utmost commitment to safety.

Book An Appointment

Frequently Asked Questions

How quickly will I see results from Re20 Fine treatment?

You may notice a subtle refreshed look within days, but Re20 Fine is a rebuilding treatment — texture refines over 2–4 weeks, and firmness, brightness and dark-circle improvement continue to develop over 6–12 weeks as your own collagen rebuilds. Many patients feel it looks best around the 6-week mark.

How long do the results from Re20 Fine treatment last?

Because Re20 Fine improves the skin's own structure rather than only adding gel, results are progressive and durable. Following a recommended course, many patients maintain a firmer, revitalised under-eye for around a year or more. Longevity varies with age, skin condition and lifestyle; your doctor will discuss a maintenance plan.

How long is each Re20 Fine treatment session?

A session typically takes around 30–45 minutes including consultation and numbing. Topical anaesthetic cream is applied first for comfort, and you can return to most daily activities immediately after.

How often should I do Re20 Fine treatment?

Many patients are advised a short initial course spaced a few weeks apart to build the result, followed by periodic maintenance. Some concerns respond well to a single session. This is personalised at consultation.

Is Re20 Fine treatment painful?

Most describe it as very tolerable. Numbing cream is applied beforehand, and because the particles are ultra-fine, the material passes through tissue with less resistance and discomfort than coarser boosters. Many rate Re20 around 2/10 on a pain scale.

Are there any side effects with Re20 Fine treatment?

Side effects are generally mild and temporary — minor redness, small injection-point bumps or slight tenderness that typically settle within 24–72 hours. Light bruising is possible depending on your capillary structure. Because there is no BDDE crosslinker, inflammatory reaction risk is low, and Tyndall tint is not typically seen at correct injection depth.

Is there any downtime with Re20 Fine treatment?

Minimal. Most patients return to work and social activities the same or next day. Makeup can usually be applied the following day. Avoid strenuous exercise, saunas, steam rooms and alcohol for 24–48 hours.

Can I combine Re20 Fine treatment with other treatments?

Yes — and it's often recommended. Re20 Fine pairs especially well with PEG-HA filler in our RE-NEAU™ under-eye protocol, and complements energy-based skin treatments and anti-wrinkle injections. Because it strengthens the ECM foundation, it can enhance the results of many other treatments. Your doctor will advise on sequencing.

What is the cost of Re20 Fine treatment?

Pricing depends on the areas treated and the amount of product used, so it's confirmed during your consultation once your doctor has assessed your anatomy and goals. You'll receive a clear quote before any treatment begins.

How can I book a Re20 Fine treatment?

Simply click the "Book Appointment" button on this page or WhatsApp us directly. Our friendly team will guide you through the next steps.