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Medical Precision,
Refined
Body Shaping
Non-surgical Approach
Fat Reduction
Featuring Cooltech Define
Medical Weight Loss:
GLP-1 Injections
Doctor-led
Assessed, Dosed & Monitored
By Registered Doctors
Doctor-led
Assessed, Dosed &
Monitored By
Registered Doctors
Weight + Face
Muscle and Facial Volume
Protected Together
Weight + Face
Muscle and Facial
Volume Protected
Together
Honest Consultation
We'll Tell You If You Don't
Need It
Honest
Consultation
We'll Tell You If You
Don't Need It
Your body defends its fat stores by turning hunger up and metabolism down.
GLP-1 weight-loss injections quieten the hunger so a calorie deficit finally holds — and our doctors protect your muscle and your face while you get there.
Natural hunger: After a meal the "I've had enough" signal fades within minutes, so hunger spikes back between meals — the food noise that drives snacking.
On GLP-1: The engineered copy lasts for days, so fullness stays switched on and the spikes flatten. Eating less feels like wanting less, not white-knuckle willpower.
Your body defends its fat stores by turning hunger up and metabolism down.
GLP-1 weight-loss injections quieten the hunger so a calorie deficit finally holds — and our doctors protect your muscle and your face while you get there.
Excess weight isn't a discipline problem — it's a defended system. As you diet, appetite hormones climb and your metabolism quietly slows, so the meals that once worked stop working. Telling someone in that state to try harder is like telling someone short-sighted to squint more sincerely.
In the weight-loss trials, the groups who dieted with real counselling but no medication lost only about 2–3% of their body weight — against roughly 15–22% with a GLP-1 injection alongside the same diet and activity. That gap is physiology, not effort.
Figures are averages from large supervised trials (STEP and SURMOUNT programmes), included alongside nutrition and activity counselling. Individual results vary widely and no outcome is guaranteed.
What Are GLP-1 Injections?
What Are
GLP-1 Injections?
GLP-1 weight-loss injections are prescription medicines that mimic a natural gut hormone released after eating. They reduce appetite, slow how quickly the stomach empties and increase fullness — so you eat less without fighting constant hunger. In Singapore they're prescribed and supervised by a doctor, never sold over the counter.
The class is known as GLP-1 receptor agonists (in Chinese, 减肥针 — jiǎnféi zhēn, "weight-loss injection"). The two used most for weight are semaglutide, given weekly, and the newer tirzepatide, which copies two gut hormones at once and tends to produce larger average loss; a daily option, liraglutide, also exists. Which one suits you — and at what dose — is a decision for your doctor, not something to assume in advance. What matters far more than the specific medicine is being properly assessed, correctly dosed and monitored.
How Do GLP-1 Injections Work?
Natural GLP-1 lasts only minutes; these medicines are engineered copies that last for days, so the "I've had enough" signal stays switched on instead of fading between meals. The honest way to picture it: losing weight is remodelling a building, not demolishing it.
It quietly removes the relentless hunger and food noise — the single biggest thing standing between you and a deficit you can actually hold.
Protein and resistance training tell the body to give up fat, not muscle. Roughly 1.2–1.6 g of protein per kg a day, and lifting 2–4 times a week.
Muscle kept is metabolism kept — the engine you'll need when you step down the dose. That's remodelling that stays up, not a crash that collapses.
What to Expect From GLP-1 Injections?
How much, how fast — and how to know it's working.
How much, how fast —
and how to know it's working.
In supervised trials, average loss ranged from about 15% of body weight with semaglutide to around 20% or more with tirzepatide over roughly 15 months, alongside diet and activity. Results build in phases: appetite settles in the first couple of weeks, visible change by weeks 8–12 as the dose builds, and the steepest loss usually between months three and six.
Appetite settles
Visible change as the dose builds
Steepest loss usually happens here
Trial averages reported from supervised programmes
Is it working?
Aim for roughly 0.5–1% of body weight per week, or about 5% over three months.
Below that on a correct dose, we review the plan rather than pushing you to eat less.
Trial averages from supervised programmes; individual results vary considerably and are not guaranteed.
Efficacy figures describe the medicine class in published trials, not a specific clinic outcome.
Trial averages from supervised programmes; individual results vary considerably and are not guaranteed. Efficacy figures describe the medicine class in published trials, not a specific clinic outcome.
Are GLP-1 Injections Suitable For You?
Usually a good fit
Adults whose weight is affecting their health — a raised BMI with issues such as prediabetes or insulin resistance, fatty liver, high blood pressure or sleep apnoea.
People who've genuinely tried and found their biology fighting back — regain, plateaus, relentless hunger.
Anyone who wants it done properly: assessed, dosed slowly, monitored, with muscle and face protected.
Not suitable / needs caution
Personal or family history of medullary thyroid carcinoma or MEN2.
A history of pancreatitis, or type 1 diabetes.
Significant gut conditions such as gastroparesis.
Pregnancy or breastfeeding.
Anyone who simply doesn't need it — we'll say so.
Side Effects of GLP-1 Injections
Side Effects of
GLP-1 Injections
Mostly mild, mostly early, mostly manageable.
Most side effects are gastrointestinal, mild to moderate, and concentrated while the dose is being raised.
Our guiding rule is simple: the dose that works with the fewest side effects is the right dose.
Most side effects are gastrointestinal, mild to moderate, and concentrated while the dose is being raised. Our guiding rule is simple: the dose that works with the fewest side effects is the right dose.
Driven by slower stomach emptying, worst during dose increases. Controlled by titrating slowly, smaller lower-fat meals, and stopping at the first sign of fullness.
Slowed gut motility can push either way. Adequate fibre, fluids and a tweaked titration handle most cases.
Usually a sign of under-eating or dehydration — the fix is more protein and water, not eating even less.
A fine, short needle sits just under the skin — a light pinch at most, and essentially painless with a few seconds of ice. The needle is the easy part.
Rarer risks (such as pancreatitis and gallstones, the latter linked to rapid weight loss of any kind) are exactly why proper screening, slow titration and monitoring matter — and why these medicines should never be bought unsupervised.
The reasons that matter are invisible in the mirror.
Excess weight — and the insulin resistance that usually travels with it — is an upstream driver of disease.
Losing 15–20% of body weight can move a person out of several risk categories at once.
In Singapore, where around one in ten adults lives with obesity, we treat this as medical weight management.
Excess weight — and the insulin resistance that usually travels with it — is an upstream driver of disease.
Losing 15–20% of body weight can move a person out of several risk categories at once. In Singapore, where around one in ten adults lives with obesity, we treat this as medical weight management.
Type 2 diabetes
High blood pressure
Abnormal cholesterol
Insulin resistance
Fatty liver
Sleep apnea
Cardiovascular disease
Osteoarthritis
PCOS & fertility
Beyond GLP-1 Injections,
Your Face Needs A Plan of Its Own
Rapid loss deflates the facial fat pads faster than skin can retract — the hollow, gaunt look popularly called "Ozempic face". It isn't the medicine damaging your skin; it's the fat loss you wanted, appearing somewhere you didn't. It's predictable, which means it's plannable — ideally started before a hollowed face appears, not after.
Rapid loss deflates the facial fat pads faster than skin can retract — the hollow, gaunt look popularly called "Ozempic face".
It isn't the medicine damaging your skin; it's the fat loss you wanted, appearing somewhere you didn't. It's predictable, which means it's plannable — ideally started before a hollowed face appears, not after.
What We Pair With
Celluject Scar
For Comprehensive Results
Our Approach at OZ
History, suitability screening, baseline bloods and a body-composition scan before anything is prescribed.
Titrated to the lowest effective dose and reviewed regularly — medicine, not a product over a counter.
Protein and resistance guidance with body-composition tracking, so what you lose is fat.
Volume and collagen sequenced early and dosed conservatively — natural, not over-filled.
A Korean board-certified dermatologist and founder of the Ozhean Skin and Plastic Surgery Network, she has authored over 30 scientific papers and created the SKIN FIT program, which has helped over 20,000 patients achieve radiant, healthy skin. She believes in personalised, evidence-based treatments that enhance natural beauty and is proud to bring the Ozhean philosophy to Singapore.
A seasoned aesthetic physician with a strong surgical foundation, he has over 15 years of medical experience spanning multiple subspecialties. Trained under the National Healthcare Group and holding postgraduate surgical qualifications, his practice is grounded in precision, anatomical accuracy, and safety. He focuses on facial harmony, structural refinement, and collagen-based regenerative treatments, with a philosophy centred on thoughtful decision-making, conservative execution, and long-term, natural ageing.
A dedicated physician with a background in family medicine, ENT, anaesthesia, dermatology, and aesthetic medicine. With experience in clinical dermatology, facial reconstruction, and collagen-based treatments, he focuses on anti-aging and long-term skin health. He believes in personalised and holistic care, combining medical expertise with artistic sensibility to support each patient’s confidence and well-being.
Dr. Tan Jun Yang is an aesthetic physician with a clinical background spanning Cardiothoracic Surgery, Anaesthesia, General Surgery, and Dermatology. His time at the National Heart Centre Singapore and the National University Hospital Heart Centre gave him extensive surgical training in complex heart and lung conditions as well as post-operative reconstructive procedures, a depth of experience that allows him to deliver results with confidence, consistency, and the utmost commitment to safety.
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