Celluject Scar

What is Celluject Scar Treatment?

Treatment designed for scars (including acne scars) and post surgical fibrosis. Acts directly on the fibrous scar tissue improving patient’s appearance and functionality.

Celluject Scar - how does it work?

Synergy Effect of the enzymatic system along with the HMW-HA, combined with the use of high-molecular hyaluronic acid.

Dispersion effect of Lyase PB72K

Liase PB72K

Degrades polysaccharide molecules responsible for fluid retention.
Promotes fluid drainage from intercellular tissue.
Increases connective tissue permeability.
Improves the dispersion of active ingredients in the area of application.

Anti-fibrotic effect of Collagenase G/H PB220

Collagenase G/H PB220

Degradation fibrotic septum

Tissue remodeling in scars

Hypertrophic

Normal

Stimulation of collagen synthesis

Effect of PB500 Lipase on the Adipose panniculus

Lipase PB500

Reduction of adipose panniculus volume.
Emptying of the adipocyte without tissue damage.
Recombinant lipase is not hormone-sensitive.

Malar fat obtained after surgery, before and after Lipase application.

Joint effects of all 3 components will lead to resolution of existing scar tissue and new healthy collagen production resulting in a more normal skin after.

Lipase

Responsible for the breakdown of fat tissue around the scars.

Lyase

Hydrolysis of the proteoglycan and the spread of the products.

Collagenase (main ingredient)

Will lead to the breakdown of excessive scar collagen. After which our tissue will replace the treated area with new healthy collagen.

All 3 products are combined with high molecular weight hyaluronic acid that helps an environment that optimises healing and enhances the effect of the previous 3 components.

Mechanism of Action

Why do we apply the 3 enzymes together?

Synergistic effect

Recombinant Enzymes Technology

Origin of enzymes

Purification

Animal

Vegetal

Low Purity.
Low Productivity.
Industrial applications.

Fermentation

Bacterial

Yeast

Intermediate productivity.
Application in food and cosmetic industries.

Genetic Engineering

Recombinant enzymes

High Purity.
High Productivity.
Medical applications

Amounts of enzyme with a very high level of purity

The enzymes are made via genetic engineering with recombinant technology to product high purity and grade of enzymes compatible for human treatments.

The company behind the product

About Proteos Biotech

Proteos Biotech is a biotechnology company that develops products for the medical and pharmaceutical industry.

Recombinant enzymes specifically designed for medical applications.
Pharmaceutical plant certified under GMP and GLP standards for the manufacture of sterile injectable medical devices by the AEMPS.
R&D and biotechnological development laboratories for the innovation of processes and products in the dermatological, clinical and aesthetic fields.

Pharmaceutical plant / Highly qualified team
Innovative and safe processes

ISO 13485 Certification

Class III Medical device manufacturing process.

Chemical Subcision

Scar tissue tethers the skin in wards forming an unattractive depressive scar on the skin
Traditionally it is treated with “physicial subcision”. That involves administering a charp needle to the scar tissue and the scar tissues are subcised , releasing the scar.
Pitfalls of physician subcision is that it is painful and often involve bruising.
Chemical subcision is revolutionary concept
Involve mico injections of collagenase into the scar tissue
Resolution of the scar tissue and releases them
Without the pain and bruising and long recoveries associated with physician subcision

How is the procedure performed?

1 Celluject scar components are first mixed by our doctors.

2 Micro injections of the products strategically on and around the scar tissues performed by the doctors

3 Quick procedure in less than 15 mins.

4 One can expect mid redness after the treatment

Clinical results

Anti-fibrotic effect of HMW-HA

Fibrosis rate after the injection of HMWHA (high molecular weight hyaluronic acid), LMWHA (low molecular weight hyaluronic acid) and in the control group.

Expression of fibrosis marker levels after application of HMWHA and LMWHA vs control group.

FAQS

How many sessions do I need?

Recommended 2-4 sessions 15 days apart. (depending on the severity of scarring)
You should see noticeable results 15 days after each treatment.

Side Effects

General Recommendations

Do not refrigerate. Use is recommended after reconstitution.
Do not perform another treatment with any device immediately after application of the enzymatic system.
Side effects are very rare, when they occur they are mild and may be erythema, edema, pain and bruises at the zone of application and general discomfort; which subside with non-steroidal anti-inflammatory analgesics (NSAIDS) treatment.

Contraindications

Pregnancy and breastfeeding.
History of allergies or idiosyncrasies to hyaluronic acid or any of the enzymes.
Cancer treatment (active or in the last 6 months).
Active autoinmune diseases.
Active atopy and asthma.
Local or systemic infection.
Irritated and damaged skin.
Coagulation problems or anticoagulant treatment in progress.
Wait at least 15 days after receiving any vaccine.

Post treatment advice

Post-treatment Advice

Reduce carbohydrate intake and avoid excess fats, maintain good hydration and keep regular physical activity.
Avoid intense exercise for the first 48 hours.
Do not apply cold compresses or ice.
Avoid swimming pools and saunas for 1 week. Apply photoprotector (+50 SPF).
Apply pbserum Easy Touch products as daily homecare maintenance.
Wait at least 15 days before starting another therapy (fillers, botox, threads, etc.)

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