Despite common sayings about "ageing gracefully", the truth is that the ageing process can be far from kind. As we grow older, our skin loses its youthful plumpness, elasticity, and structure. The decline of collagen production — starting as early as our 20s — means that the skin becomes thinner and looser over time. But it’s not just the skin that changes.

Deeper structures of the face also lose support. Fat pads shrink and descend, the SMAS layer (Superficial Musculoaponeurotic System) weakens, and the retaining ligaments that once held the facial tissues in place become lax. As a result, folds and lines begin to appear, especially around the nasolabial area (NLF), marionette lines, and jawline. These changes are often the most obvious visual markers of ageing.

For decades, the common solution for reversing these changes was the surgical facelift. By surgically lifting and tightening both the skin and the underlying SMAS layer, a facelift could restore youthful contours. However, this approach comes with consideration of factors like:

• Surgical incisions and scarring
• Lengthy recovery time
• Post-operative pain
• Potential for anaesthesia-related risks
• And, critically, results that heavily depend on the surgeon’s skill.

Understandably, not everyone is ready—or willing—to undergo such an invasive procedure.

Fortunately, advancements in non-surgical face lifting have created minimally invasive alternatives: Thread Lifts, HIFU, and Ultherapy. But how do these compare to each other and to the traditional facelift?

The Rise of Non-Surgical Face Lifting

What if you could achieve a lifted, youthful appearance without surgery?

That question has driven the development of non-invasive and minimally invasive skin lifting technologies over the last two decades. The demand for effective solutions with minimal downtime has led to treatments that tighten skin, stimulate collagen, and, in some cases, physically reposition sagging tissues.

Today, three of the most popular non-surgical face-lifting methods are:

1. Thread Lifts
2. HIFU (High-Intensity Focused Ultrasound)
3. Ultherapy (Microfocused Ultrasound with Visualisation)

Which is right for you? Let’s break down how they work, what to expect, and how they compare.

Thread Lift: The Mechanical and Biological Approach

A thread lift involves the insertion of fine, medical-grade sutures beneath the skin using a tiny needle or cannula. These threads, made from absorbable materials like PDO, PLLA, or PCL, are designed with either barbs or cones. Once inserted, the threads hook onto the underlying tissue, allowing the practitioner to gently pull the skin upward, repositioning sagging areas like the jawline, cheeks, brows, and neck.

But the benefits go beyond visible lifting. As the threads settle into place, they stimulate the body’s natural healing response, boosting collagen production in the surrounding tissues. This collagen stimulation provides long-term improvement in skin firmness and elasticity, even after the threads have dissolved.

Key Benefits of Thread Lifts:

• Lifting effect
• Long-term collagen stimulation
• Customisable to different facial areas
• Minimal downtimex
• Results lasting 6 months to 2 years

Thread lifts are particularly effective for patients seeking visible, physical lifting without undergoing surgery. Other threads, such as moulded barbs or ultrasound-moulded threads, offer better tension.

However, thread lifts are not ideal for everyone. Individuals with severe skin laxity or very thin skin may not achieve the desired results and could be better candidates for surgical intervention or combined therapies.

HIFU: The Power of Ultrasound Energy

High-Intensity Focused Ultrasound (HIFU) is a non-invasive skin lifting technology that uses focused ultrasound energy to heat the deeper layers of the skin and SMAS. By delivering thermal injury points, HIFU triggers the body’s natural wound healing response, leading to collagen remodelling and skin tightening over time.

HIFU stimulates internal tightening by:

• Contracting collagen fibres
• Promoting neocollagenesis (new collagen production)
• Increasing skin elasticity

Key Benefits of HIFU:

• Non-invasive — no needles or cuts
• Safe for most skin types
• Gradual, natural-looking results
• Minimal downtime
• Results lasting 6 to 12 months

HIFU is ideal for individuals with mild to moderate skin laxity who prefer a needle-free option. However, the lifting effect is subtle compared to thread lifts or surgery. It’s suitable for early signs of ageing or for maintaining results after other lifting treatments.

Ultherapy: Accurate Lifting with Visualisation

Ultherapy combines micro-focused ultrasound with real-time ultrasound imaging (visualisation). This allows practitioners to see exactly where the energy is being delivered — ensuring accurate targeting of the SMAS layer and optimising treatment outcomes.

Like HIFU, Ultherapy works by heating the deeper skin layers, stimulating collagen production and causing tissue contraction. Ultherapy is able to:

• Customise treatment depth (superficial dermis to deep SMAS)
• Avoid critical structures using ultrasound imaging
• Achieve consistent results

Key Benefits of Ultherapy:

• Non-invasive with minimal downtime
• FDA-cleared for lifting the brow, chin, and neck
• Real-time visualisation for enhanced safety and efficacy
• Gradual, natural-looking improvements
• Results lasting up to 12 to 18 months

Ultherapy is ideal for patients with early to moderate signs of skin laxity who desire a natural lift without needles or surgery.

Comparing Thread Lift, HIFU, and Ultherapy

Key Takeaways:

• Thread lifts deliver the visible lift.
• HIFU provides subtle tightening without needles — ideal for early ageing.
• Ultherapy offers a customisable tightening effect with deep collagen stimulation.
  

Can They Be Combined?

Absolutely. In fact, many patients achieve their aesthetic goals by combining these treatments.

• Thread lifts provide a quick lift and structural support.
• Ultherapy or HIFU can be used before or after threads to enhance collagen production and maintain results.
• Injectable collagen stimulators (e.g., CaHA Filler, PDLLA Filler) or HA fillers can restore volume where needed, complementing the lifting effect.
  

This multi-layered approach addresses skin laxity, volume loss, and structural support, creating a comprehensive and lasting facial rejuvenation.

Are There Cases Where Non-Surgical Lifting Is Not Enough?

Yes. While non-surgical face-lifting methods show results for many patients, they do have limitations.

Patients who may not be ideal candidates include:

• Individuals aged 70 and above with severe skin laxity and visible ageing effects.
• Patients with significant volume loss, where threads or energy devices cannot provide sufficient lifting or volume restoration.
• Those needing extensive tissue repositioning, where a surgical facelift remains the effective solution.

Thread lifts, HIFU, and Ultherapy can’t do it all. They are ideal for patients with mild to moderate skin sagging or those seeking to maintain or enhance the results of previous lifting treatments.

Final Thoughts: Which Skin Lifting Treatment Is Suitable for You?

The answer depends on your age, degree of skin laxity, treatment goals, and tolerance for downtime.

• If you want visible lifting, especially for moderate sagging: Thread Lift.
• If you prefer no needles and gradual tightening for mild laxity: HIFU.
• If you desire accurate lifting with deeper collagen stimulation and minimal downtime: Ultherapy.

Ultimately, a suitable approach for your skin may involve a personalised combination of treatments to address both lifting and volume loss, tailored to your anatomy and aesthetic goals.

Book a Consultation with Ozhean Zoey Today

Not sure which treatment is right for you? Contact Ozhean Zoey today to schedule your personalised consultation and discover how to lift, tighten, and rejuvenate your face — without surgery.

A radiant, even-toned complexion often signals beauty and youthfulness. In Singapore’s warm and sunny climate, many individuals seek treatments that reduce pigmentation, correct uneven tone, and boost skin luminosity.

That’s where skin whitening or brightening treatments come in. This article explores these treatments, what to expect, and how to start your journey toward glowing skin.

How Skin Lightening and Whitening Treatments Improve Skin Appearance

Skin whitening treatments primarily work by inhibiting melanin production or accelerating the removal of pigmented cells. Melanin is the natural pigment that gives your skin its colour; however, excessive sun exposure, inflammation, or hormonal changes can trigger overproduction, leading to uneven skin tone and dark spots.

These treatments work by:

• Suppressing tyrosinase, the enzyme that drives melanin production.
  
• Promoting cellular turnover to eliminate pigmented cells.
  
• Boosting antioxidant levels to fight free radicals that dull and age the skin.
  

Topical and Oral Solutions

Topical Creams and Serums

If you want subtle improvements, start with topical products. These creams and serums usually contain active ingredients like the ones we mentioned earlier. With consistent application over several weeks or months, you’ll gradually see results.

Oral Supplements

Many people in Singapore now turn to oral supplements like glutathione, collagen, and vitamin C to enhance skin tone from within. Although convenient, the effectiveness of these supplements depends on dosage, bioavailability, and your metabolism. To improve results, you can combine supplements with a consistent skincare routine and professional treatments.

Types of Professional Treatments

If you're aiming for effective results, you should consider professional aesthetic treatments. At Ozhean Zoey, skin whitening isn’t about drastically altering your skin tone—it’s about achieving bright, clear, and healthy-looking skin safely. Here’s what we offer:

1. Pico Laser (with Pico Toning)

This laser treatment uses photoacoustic energy to break down superficial pigmentation safely and effectively. It also improves skin texture, stimulates collagen production, and reduces fine lines, acne scars, and dullness—all without damaging surrounding skin.

2. ProYellow Laser

This laser targets both melanin and haemoglobin, making it effective for brightening skin, reducing redness, and improving overall skin clarity. It’s especially popular among patients seeking the “glass skin” glow.

3. Q-Switch Laser

Q-Switch Laser, in long-pulse mode, penetrates deeper layers of skin to treat stubborn pigmentation. It’s often used for melasma and dermal hyperpigmentation, offering gradual but visible improvements.

4. RF Microneedling

This microneedling radiofrequency treatment remodels the deeper layers of skin, boosting collagen and improving overall skin health. When combined with other whitening treatments, it enhances absorption and efficacy, making it ideal for long-term brightening results.

5. LDM Treatment

Using dual-frequency ultrasound waves, LDM promotes skin healing, reduces inflammation and redness, and improves dermal structure. It’s ideal for patients with sensitive skin or those looking for gentle but effective whitening support.

Quinta Laser Programme by Ozhean Zoey

If you’re seeking a comprehensive skin solution that helps with skin lightening and whitening while also tackling sagging, scarring and wrinkles, you can consider Ozhean Zoey’s Quinta Laser Programme. It brings together in one treatment five laser technologies: Yellow Laser, Long Pulse Laser, Q-Switched Nano Laser, Pico Laser and CO2 Laser.

Each laser is carefully selected and calibrated to complement the others, creating a synergistic effect that enhances overall skin clarity and vitality.

Cost of Skin Lightening and Brightening Treatments in Singapore

In Singapore, the cost of skin lightening, whitening, and brightening treatments can vary depending on several key factors. Whether you're considering topical products, oral supplements or in-clinic procedures, understanding what influences the price can help you make informed choices that align with both your goals and your budget.

Factors Affecting the Cost

• Type of treatment: Topical creams may start from $30, while laser sessions can range from $200 to $600 each.
  
• Clinic reputation: Well-known clinics with experienced doctors typically charge more.
  
• Technology used: Machine treatments like Pico or CO2 fractional lasers usually cost more.
  
• Number of sessions: More severe pigmentation may require multiple sessions.
  
• Customisation: Personalised treatment plans combining lasers, serums, and post-care will affect your total cost.
  

Looking for Skin Brightening, Whitening, and Lightening Treatments?

Radiant, even-toned skin is an achievable goal. With the right guidance, you can explore skin lightening, whitening, and brightening treatments that are tailored to your skin type and aesthetic goals.

Ozhean Zoey is ready to be your guide. Our doctors start with a thorough skin analysis before recommending any treatment plan. Book an appointment today to take the first step toward luminous, even-toned skin.

Frequently Asked Questions

How long do the results of skin whitening treatments last?

With consistent use, topical treatments typically show results in 4–8 weeks. Laser treatments or injectables often deliver faster results, though you’ll need periodic maintenance to sustain the effects. Your lifestyle habits—such as sun protection and consistent skincare—determine the long-term success of your treatment.

Are skin brightening and lightening treatments safe for sensitive skin?

Yes, but choosing the right treatment is key. Gentle options like niacinamide serums or low-intensity lasers usually suit sensitive skin. Always consult a qualified aesthetic doctor who can assess your skin and recommend a personalised plan.

Can skin whitening treatments also help with acne scars?

Yes. Many skin whitening and brightening treatments, especially lasers and active ingredients like vitamin C and tranexamic acid, can fade acne scars. By encouraging cell turnover and collagen production, these treatments improve your skin’s texture and tone.

In recent years, the thread lift has emerged as a sought-after aesthetic treatment, bridging the gap between non-surgical procedures and the surgical facelift. The results include: skin firmness, lifting and definition, without the long scars, extensive downtime, or the risks linked to surgery and general anaesthesia.

At Ozhean Zoey, thread lift procedures are performed under local anaesthesia for patient comfort. This minimally invasive approach means most individuals tolerate the procedure well, returning quickly to their daily activities.

Yet, while thread lifts show results, the most common question remains: how long do these results last?

Longevity: A Common Concern Among Thread Lift Patients

Some individuals who have undergone thread lifts report a loss of results within just three to six months. At Ozhean Zoey, we bring years of experience using multiple thread brands, including Happy Lift, Silhouette Lift, Serdev Threads, and Korean-developed threads like Art Lift and MINT Lift. Over the years, we have refined our approach and developed our proprietary OLLYA threads, which have consistently demonstrated effective results lasting between 6 and 12 months. In many cases, they may last up to 24 months or more.

But what determines how long a thread lift lasts? Let’s explore the key factors.

1️⃣ Thread Concept: Anchoring Threads and Floating Threads

Anchoring threads provide a sustained lift. They are secured into deep tissues (sometimes even periosteal or bone fixation in older designs), ensuring that facial movements do not easily displace them.

In contrast, floating threads tend to lose tension over time due to facial expressions and natural tissue movements. While they may offer some plumping effects, such as fuller cheeks, their lifting power diminishes relatively quickly.

2️⃣ Thread Design: Needle Threads and Cannula Threads

Needle threads, including our OLLYA Lift, permit the use of long threads that engage a sizeable area of sagging tissue. This provides a strong and enduring lift.

Cannula threads, which include designs like single thread, spring, tornado, and cockscrew (previously common for volumisation), offer less trauma upon insertion but can be more uncomfortable during the procedure. At Ozhean Zoey, we strategically use single cannula threads to enhance structural support for OLLYA threads rather than relying solely on them for lifting.

With the rise of injectable collagen biostimulators such as CaHA Filler, PCL Filler, and PDLLA Filler, the need for collagen-stimulating solid threads like tornado or spring designs has decreased. Today, these injectables often replace the volumising role of older thread types.

3️⃣ Thread Hooks: Cones and Barbs; Cut Cogs and Moulded Cogs

In the aesthetic field today, doctors use ultrasound-moulded threads, like the Double-Fix system. These threads avoid heat moulding, preserving both thread strength and barb integrity. They can support tissue loads of up to 4.5 kg—offering a strong and durable lift without adding unnecessary bulk.

4️⃣ Material Matters: PDO, PLLA and PCL

PDO threads are common for their collagen stimulation but have a relatively short lifting lifespan. PLLA threads tend to last but are prone to breakage under tension. PCL threads, especially those used in Ozhean Zoey’s OLLYA system, combine longevity with effective collagen induction, providing the longest-lasting lifts available today.

5️⃣ Ozhean Zoey’s OLLYA Threads

At Ozhean Zoey, we recognised the limitations of existing threads and created the OLLYA Thread System.

Features of OLLYA Threads:

Patients enjoy not only visible improvement but also ongoing rejuvenation as collagen continues to build over time.

🔎 What’s Next for Thread Lifting?

TESSLIFT: Combined Lifting and Volumisation

This design merges a 3D mesh scaffold with barbed (cogged) threads. The mesh encourages tissue ingrowth and collagen production, offering not just lifting but also volumisation, addressing two patient concerns in one treatment.

By combining structure and support, the TESSLIFT offers near- and long-term benefits.

Heat-Responsive Threads

These threads are designed to contract when exposed to heat, such as from High-Intensity Focused Ultrasound (HIFU) treatments.

The goal is to create a thread that:

• Tightens during HIFU sessions, enhancing lift without requiring repeat thread placements.
  
• Extends the lifespan of thread lifts, reducing the frequency of treatments.
  

Though still in the experimental phase, this thread could change the way we maintain lifting results over time.

Final Thoughts: Choosing the Right Threads for Lasting Beauty

So, how long does a thread lift last? The answer depends on multiple factors: the type of thread, its design, the anchoring method, and the material used. At Ozhean Zoey, thanks to Dr. Park’s input and our OLLYA system, we are committed to delivering thread lift results that last, typically 12 to 24 months or even longer for some patients.

With the TESSLIFT and other technologies such as heat-responsive threads, patients can expect longer-lasting and less invasive rejuvenation options in the years to come.

If you are considering a thread lift and want sustained beauty, a consultation with a skilled and experienced provider is essential. Our team at Ozhean Zoey is ready to help.

Ready to Experience the Power of OLLYA Threads?

Contact Ozhean Zoey today to schedule your personalised consultation and discover how a thread lift can redefine your beauty and restore youthful confidence, without surgery.

In today’s fast-paced professional world, many individuals want to maintain a refreshed, youthful appearance without sacrificing valuable work time or personal commitments. Traditional cosmetic surgery, with its extensive downtime, is no longer the preferred option for most. That’s why non-invasive skin lifting treatments like Ultherapy have gained massive popularity, especially among busy professionals.

Ultherapy Prime, the modern version of Ultherapy, was developed by Merz Aesthetics and launched in late 2024. It was designed to improve treatment times, imaging, energy delivery and patient comfort.

For time-strapped working adults, Ultherapy Prime offers a convenient, effective way to lift and tighten skin, often completed during a lunch break.

How Does Ultherapy Prime Work?

Ultherapy Prime harnesses micro-focused ultrasound with visualisation (MFU-V) to deliver targeted energy beneath the skin’s surface. This energy heats the Superficial Musculoaponeurotic System (SMAS) layer—the same foundational layer targeted by surgical facelifts. The heat stimulates the body’s natural collagen production, gradually lifting and tightening the skin over three to six months.

The real-time visualisation feature of Ultherapy Prime, which includes a 35% larger and sharper imaging screen, allows the practitioner to see exactly where the energy is being delivered. This improves targeting, consistency, and the safety of the procedure.

The Lunchtime Lift: Quick, Comfortable, and Effective

One feature of Ultherapy Prime is its ability to provide a "lunchtime lift". This nickname comes from how easily the treatment can be done within a typical lunch break, making it ideal for busy professionals.

Why is Ultherapy Prime considered a lunchtime procedure?

• Faster treatment time: Most sessions take 30 to 45 minutes, depending on the treatment areas.
  
• Minimal discomfort: Improved energy delivery and modernised treatment protocols have reduced discomfort significantly.
  
• Minimal downtime: Patients can return to work or other activities immediately after the procedure.
  
• Natural results: Results appear gradually over the next few months, avoiding the “overdone” look and ensuring a natural transformation.
  

These benefits make Ultherapy Prime an easy addition to even the busiest professional’s schedule.

What Happens During the Treatment Process?

At Ozhean Zoey Medical & Aesthetic Clinic, we have designed a streamlined process to maximise your results and minimise treatment time.

Step 1: Comprehensive Facial Analysis Using Quantificare Imaging

Your journey begins with a 3D facial analysis using Quantificare’s LifeViz® Mini system. Quantificare is a medical imaging system that creates accurate, three-dimensional images of your face. It helps the clinician evaluate skin texture, laxity, volume loss, wrinkles, and other signs of ageing.

This customised analysis allows us to map out ageing patterns, identify treatment areas, and tailor the Ultherapy Prime session to your facial anatomy and goals.

Step 2: Application of Numbing Cream

To enhance comfort, a topical numbing cream is applied before treatment. This step typically overlaps with the facial analysis to avoid unnecessary waiting time.

Step 3: Consultation with the Doctor

Before the procedure, you will meet with our experienced doctor to review the treatment plan, discuss what to expect, and answer any remaining questions.

Step 4: Ultherapy Prime Treatment

Using the imaging system, the doctor delivers targeted ultrasound energy to the mapped treatment areas. The treatment usually lasts 30 to 45 minutes, with most patients reporting minimal discomfort.

Step 5: Quick Post-Treatment Care

After the procedure, we apply sunblock to protect the treated areas, and you are free to return to your day without restrictions.

Patient Satisfaction: Clinical Evidence Speaks Volumes

The efficacy of Ultherapy and Ultherapy Prime is supported by an extensive body of clinical research.

• 95% of patients reported satisfaction with Ultherapy results one year post-treatment, according to data published on Ultherapy’s official website.
  
• Ultherapy is backed by over 50 clinical studies and more than 120 peer-reviewed publications.
  
• Globally, over 3 million Ultherapy treatments have been performed, underscoring its safety and effectiveness.
  
• Studies, including one published in the Journal of Clinical and Aesthetic Dermatology, reported that 95% of patients experienced visible improvement in skin laxity and lifting at one year post-treatment.
  
• Research published by the National Institutes of Health (NIH) revealed that many patients perceived a reduction in apparent age following Ultherapy treatment, alongside noticeable improvements in facial and neck skin characteristics.
  

Suggested Combination Treatments to Maximise Your Lunchtime Lift

For effective results, many patients combine Ultherapy Prime with other non-invasive treatments. These combinations can address multiple aspects of ageing, including skin quality, volume loss, and dynamic wrinkles.

Botulinum 

Botulinum injectables can be used to reduce dynamic wrinkles caused by muscle movements. Common treatment areas include the forehead, frown lines, and crow’s feet.

Skin Boosters (PDLLA or HA)

Skinboosters, using PDLLA (Poly-D, L-lactic acid) or Hyaluronic Acid (HA), improve skin hydration and stimulate collagen production. They enhance the skin’s texture, elasticity, and overall quality.

Collagen-Stimulating Fillers (CaHA or PDLLA)

For subtle volumization and long-term collagen stimulation, Calcium Hydroxylapatite (CaHA) or PDLLA-based fillers are ideal. These fillers restore facial volume while supporting skin tightening and lifting.

Monopolar Radiofrequency Treatment

Monopolar Radiofrequency deliver controlled bulk heating deep within the skin. This process stimulates collagen remodelling and results in faster skin tightening, with continued improvement in the following months. Monopolar Radiofrequency works within the dermal layers to enhance skin firmness and elasticity. The built-in cooling system ensures patient comfort.

Skin Tightening vs. Face Lifting: Key Differences

Skin tightening refers to improving skin firmness and elasticity, making the skin appear smooth and youthful. Face lifting focuses on repositioning sagging tissues to restore youthful contours and reverse the effects of gravity. By combining both approaches, patients can achieve comprehensive rejuvenation with natural-looking results.

Final Thoughts: The Smart Solution for Busy Professionals

Ultherapy Prime has redefined non-surgical skin lifting for individuals with demanding schedules. With shorter treatment times, minimal discomfort and downtime, and gradual, natural results, Ultherapy Prime is an ideal solution for busy professionals who want to look refreshed and confident without sacrificing valuable time.

By combining Ultherapy Prime with customised adjunct treatments such as skinboosters, collagen-stimulating fillers, and Monopolar Radiofrequency, patients can improve results while keeping a natural look.

Whether preparing for an important work presentation, a social gathering, or simply wanting to maintain a youthful appearance, Ultherapy Prime offers a convenient, effective, and clinically proven solution.

Take the Next Step: Book Your Consultation Today

At Ozhean Zoey Medical & Aesthetic Clinic, we understand the needs of busy professionals. That’s why we offer efficient, personalised treatment plans tailored to your facial anatomy, lifestyle, and aesthetic goals. Our team, led by Dr. Park Ji-youn—a member of the Global Aesthetic Leaders Club for Ultherapy Prime—is committed to delivering results with the utmost care and precision.

Contact us today to schedule your consultation and discover how Ultherapy Prime can help you achieve a youthful, confident appearance—all during your lunch break.

In the fast-paced and beauty-conscious landscape of Singapore, skin booster treatments have rapidly gained popularity as one of the effective ways to achieve swift, noticeable improvements in skin health. These minimally invasive procedures complement other aesthetic therapies such as laser and radiofrequency (RF) treatments, providing hydration, rejuvenation and anti-ageing benefits. The demand for skin boosters reflects Singaporeans' growing preference for non-surgical aesthetic solutions, which offer tangible results with minimal downtime. With an average session costing between SGD 300 to SGD 800, skin boosters represent a valuable investment for individuals keen on maintaining youthful, glowing skin.

How Do Skin Boosters Work

Skin boosters rejuvenate the skin by introducing specialised active ingredients such as hyaluronic acid (HA), Poly-D, L-lactic acid (PDLLA), and Polynucleotide (PN) directly into the skin’s deeper layers. This targeted delivery method ensures effective absorption and effectiveness, improving hydration, collagen production, and overall skin health.

These injections are typically administered manually using ultra-fine needles (32-34 gauge), minimising discomfort. Alternatively, injector guns equipped with multiple needles can be used for quicker procedures, albeit with a slightly higher risk of leakage. Both methods maintain very low pain scores, and local anaesthetics are commonly applied to further enhance patient comfort. Individuals with heightened sensitivity may opt for additional pain relief measures to ensure a pleasant treatment experience.

The three primary ingredients used in skin boosters each have distinct roles:

• Hyaluronic Acid (HA): An essential hydration molecule, HA attracts water to intensely moisturise the skin, visibly improving elasticity and texture.
• PDLLA (Poly-D, L-lactic Acid): A powerful biostimulator, PDLLA promotes the production of collagen and elastin, essential proteins for maintaining skin firmness and elasticity.
• Polynucleotide (PN): Derived from DNA compounds, PN primarily facilitates skin repair and reduces inflammation, making it effective for rejuvenating damaged skin.

Where Can Skin Boosters Be Used?

One of the major advantages of skin boosters is their versatility. These treatments effectively target multiple areas, delivering results across different regions of the body:

• Face: Skin boosters improve skin tone, hydration, and elasticity on areas such as the forehead, cheeks, under-eye regions, and jawline, diminishing fine lines and wrinkles.
• Neck: They enhance neck firmness and elasticity, combating signs of ageing that often manifest prominently in this delicate area.
• Hands: The rejuvenating effects restore hydration and plumpness, making hands appear younger and less susceptible to ageing signs.

Patients who undergo skin booster treatments notice substantial improvements across these areas, achieving visibly revitalised skin and an overall younger appearance.

Different Types of Skin Boosters

Hydration Series

The Hydration Series primarily features HA, known for its moisture-retention properties. Clinical studies (PMC10082573) demonstrate that HA significantly boosts the skin’s hydration levels, enhancing elasticity and reducing fine lines. This intense hydration improves the skin’s structural support and extracellular matrix (ECM), resulting in more youthful skin.

There are two main HA-based skin boosters:

• Non-cross-linked HA: Provides faster, intense hydration with visible effects lasting approximately 2-3 months.
• Mildly cross-linked HA + Glycerol (Belotero Revive): Scientifically proven (PubMed35070607; PMC6698156) to offer lasting results of up to 9 months, delivering sustained hydration, improved skin texture, and longer-lasting rejuvenation effects.

Collagen Series

Collagen boosters such as PDLLA enhance the skin’s natural ability to produce collagen, leading to improved firmness and elasticity. Studies (PubMed37969055; PubMed37175693) confirm improvements in skin texture, volume, and overall firmness, specifically highlighting the effectiveness of Juvelook in achieving lasting skin rejuvenation. Regular treatments result in firmer and younger-looking skin.

Healer Series

The Healer Series, featuring Polynucleotide (PN), specialises in skin repair and rejuvenation. PN’s powerful regenerative properties effectively target damaged skin, particularly from acne scarring or photodamage. Clinical research (PMC11311621) highlights PN’s ability to rejuvenate damaged skin, reduce inflammation, and enhance skin healing. Although its primary strength lies in repair, PN also moderately contributes to collagen production and hydration.

Comparative Table of Skin Boosters

Who Is Suitable for Skin Boosters?

Skin boosters are beneficial for a broad range of individuals. They are especially suited for those experiencing skin dehydration, mild sagging, fine lines, and imperfections such as acne scars. These treatments are gentle enough to accommodate sensitive skin types, making them accessible to almost everyone seeking improved skin health and appearance.

What to Expect During and After a Skin Booster Injection Treatment

The Skin Booster Injection Procedure: Step-by-Step

The skin booster injection procedure is relatively quick and straightforward:

1. Consultation: Your aesthetic doctor will assess your skin, discuss your goals, and recommend the best type of treatment.
2. Preparation: To minimise discomfort during the procedure, the treatment area will be cleaned and numbed with a topical anaesthetic.
3. Injection: The doctor will inject the skin booster into the intended areas using a fine needle. Depending on the treatment area, multiple tiny injections may be required.
4. Post-Treatment Care: After the injections, your skin may appear a little red or swollen, but these effects typically subside within a few hours.

The entire procedure spans between 30 to 60 minutes, depending on the area being treated.

Aftercare Tips and Post-Treatment Recovery

After your skin booster injection, follow these aftercare tips to ensure lasting results:

• Avoid touching or rubbing the injected site for at least 24 hours to prevent irritation.
• Stay out of direct sun exposure for 48 hours to reduce the risk of sunburn or pigmentation.
• Keep the treated area clean and follow instructions from your doctor for skin care.

You may see slight redness, swelling, or bruising, but these side effects typically resolve within a few days. There’s minimal downtime, so you can resume most of your regular activities after treatment.

How Long Does It Take to See Results from Skin Booster Injections?

You can expect initial results to be noticeable within 1–2 weeks after your treatment as your skin absorbs the hyaluronic acid and becomes more hydrated. Full results will gradually develop over the following weeks as collagen production picks up and skin texture improves.

For long-lasting benefits, we recommend maintenance treatments every 6 to 12 months, depending on the type of skin booster used and your skin concerns.

Can You Combine Different Skin Booster Products?

Absolutely. Combining various skin boosters amplifies their effects through synergistic actions:

• PDLLA + HA: Offers enhanced hydration alongside robust collagen stimulation, resulting in firmer, radiant skin.
• HA + PN: Particularly effective for acne-damaged skin, this combination provides intensive hydration and potent repair, as clinically supported (PubMed32248707), rejuvenating even severely affected skin.

The OZ Difference

At Ozhean Zoey Medical Clinic, we design various skin booster combinations for skin rejuvenation:

• Zoey Skin Combo (HA + PN + Botulinum + Tranexamic Acid): Targets multiple concerns, including pore reduction, skin whitening, and texture refinement.
• Baby Collagen (Type 1 Collagen + HA): Ensures deep hydration, enhanced skin repair, and improved skin firmness and elasticity.
• Mixed HA Protocol (Non-cross-linked HA + Cross-linked HA/Glycerol): Delivers both fast and prolonged hydration, effectively rejuvenating the skin.

Consult Ozhean Zoey Medical Clinic

Ready to experience the transformation skin boosters offer? Schedule your personalised consultation with Ozhean Zoey today and embark on your journey towards youthful, radiant, and healthier skin.

Collagen has long been celebrated as the foundation of youthful, healthy skin. As we age, collagen production in our bodies naturally declines, leading to visible signs of ageing such as fine lines, wrinkles, and sagging skin. In Singapore, where the demand for non-invasive aesthetic treatments is on the rise, collagen-based therapies have gained immense popularity for their ability to rejuvenate the skin and restore its natural glow. This comprehensive guide will help you understand the differences between collagen injections and collagen biostimulators, explore the history and science behind these treatments, and provide practical insights on choosing the right treatment for your needs.

What Is Collagen and Why Does

Collagen is the most abundant protein in the human body, making up around 30% of our total protein content. It provides structure and strength to our skin, bones, muscles, and connective tissues. In the skin, collagen gives firmness and elasticity—two key elements that contribute to a youthful appearance. Unfortunately, starting from our mid-20s, collagen production begins to slow down, and by the time we reach our 40s, we may have lost up to 25% of our skin’s collagen. This decline results in wrinkles, sagging, and a loss of volume.

To combat these effects, aesthetic medicine has developed various collagen-enhancing treatments. Among them, collagen injections and collagen biostimulators are two of the most talked-about options. Although both aim to improve collagen levels in the skin, their mechanisms, benefits, and treatment goals differ significantly.

Collagen Injections vs Collagen Biostimulators: Understanding the Difference

Collagen Injections

Collagen injections involve the administration of collagen-based products directly into the skin. These products contain processed collagen—either from bovine, porcine, or other sources—and are designed to restore volume, smooth out fine lines, and stimulate the body’s own collagen production. Historically, the earliest collagen injections used bovine-derived products like Zyderm and Zyplast. However, these were phased out due to allergic reactions and the short duration of effect.

Modern collagen injections have evolved significantly. Products such as Linerase and Deusaderm are designed to minimise allergic reactions while maximising regenerative potential. Linerase, for example, is a porcine-derived type I collagen that has undergone specific processing to reduce allergenicity. It is effective for superficial skin rejuvenation and is widely known in Singapore as the “baby collagen” treatment due to its ability to restore a soft, youthful texture to the skin.

Deusaderm, on the other hand, is a collagen filler made from porcine dermis. It uses technologies such as telopeptide removal, multifiber induction, and dual cross-linkage to mimic the properties of human collagen without the need for human tissue sourcing or donor screening. When used undiluted, Deusaderm acts as a filler for areas like tear troughs, delivering natural volume and contour. When diluted, it becomes a skin booster that enhances dermal quality and radiance.

Collagen Biostimulators

Collagen biostimulators are synthetic polymers that do not contain collagen themselves. Instead, they work by stimulating the skin to produce its collagen over time. These compounds include substances like poly-L-lactic acid (PLLA), poly-D, L-lactic acid (PDLLA), and polycaprolactone (PCL). Once injected, they create a mild inflammatory response that activates fibroblasts, the cells responsible for generating collagen.

Unlike collagen injections, which offer relatively immediate results, biostimulators take weeks to months to show their full effect. However, their results are often longer-lasting, with some products offering benefits for up to two years. Biostimulators are typically used for deeper facial volumization, structural lifting, and correcting age-related skin laxity.

The History of Collagen Injections: From Bovine to Bioengineered Breakthroughs

The use of collagen as a dermal filler dates back several decades. According to a study published in the Journal of Clinical and Aesthetic Dermatology, Zyderm and Zyplast were among the first bovine collagen fillers approved for aesthetic use. While effective, they required mandatory skin testing due to the risk of allergic reactions, and their results typically lasted only a few months.

In an effort to improve safety and longevity, researchers began exploring human-derived collagen. These included collagens extracted from human placentas, which had zero allergenic potential. However, the requirement for stringent infectious disease screening and regulatory approval limited their widespread adoption. Since 2005, no human-derived collagen filler has received global licensing in many countries.

This led to the development of new-generation collagen products like Linerase and Deusaderm. Linerase is a heterologous collagen with hypoallergenic properties, making it ideal for skin regeneration and anti-ageing treatments. Deusaderm, derived from porcine skin and enhanced through proprietary processing techniques, provides a close approximation to human collagen while eliminating the need for donor screening. Both products represent an advancement in the field of bioregenerative aesthetics.

Comparing Efficacy: Collagen Injections vs Biostimulators

While there is no direct clinical study comparing the efficacy of collagen injections versus collagen biostimulators, expert experience in the field provides valuable insights. For instance, collagen biostimulators such as PCL and PDLLA are often preferred for patients seeking deep volume restoration, particularly in the midface, temples, and jawline. These products offer long-term collagen production and a gradual, natural-looking lift.

Collagen injections, by contrast, are ideal for more superficial applications. Deusaderm, for example, is highly effective in correcting tear trough deformities and under-eye shadows with minimal swelling and a 95% correction rate. It provides an excellent alternative to hyaluronic acid (HA) fillers, especially in patients prone to puffiness or Tyndall effect.

In terms of skin quality improvement, older patients may benefit more from collagen injections like Linerase, which help restore a thinning dermis and improve skin texture. PDLLA skin boosters are often used for younger patients dealing with acne scars and enlarged pores, offering mild collagen stimulation and skin refining effects.

Not Just Injections: Devices That Act as Collagen Biostimulators

While injectables are widely recognised for their biostimulating effects, certain medical devices have also proven to be effective collagen boosters. These technologies deliver energy to the deeper layers of the skin, stimulating natural collagen production through heat or mechanical action.

1. High-Intensity Focused Ultrasound (HIFU)

HIFU, including advanced versions such as Ulthera and Ozhean’s proprietary Ultherma, works by delivering focused ultrasound energy into the SMAS (Superficial Musculoaponeurotic System) layer of the skin. This energy heats the tissue to a precise temperature, triggering a wound healing response that results in collagen production and skin tightening. The effect is a natural lift without surgery.

2. Radiofrequency Microneedling (RF-MN)

Devices like Secret RF and Sylfirm X combine microneedling with radiofrequency energy. The microneedles create controlled micro-injuries in the skin while delivering heat deep into the dermis. This dual action promotes both skin renewal and collagen induction, making RF-MN ideal for acne scars, enlarged pores, and fine lines.

3. Laser Devices

Certain fractional and non-ablative lasers also stimulate collagen by heating the dermis. Technologies such as the Mulgwang Laser or Pento Laser used at Ozhean Zoey promote brightening and collagen renewal with minimal downtime. These treatments are particularly useful when combined with injectable collagen therapies for a synergistic effect.

Why Singapore Is Turning to Collagen Therapies

In Singapore’s fast-paced and appearance-conscious society, there is a growing demand for aesthetic treatments that are safe, effective, and deliver natural results with minimal downtime. Collagen therapies fit this demand. They offer a regenerative approach to skincare, focusing on rebuilding the skin’s natural structure rather than simply masking imperfections.

Clinics such as Ozhean Zoey have built a reputation for specialising in collagen-based protocols. Their approach involves combining injectables with supportive technologies like ultrasound-based lifting, laser systems, and exosome therapy to maximise results.

Frequently Asked Questions About Collagen Treatments

Final Thoughts: Choosing the Right Treatment for You

Collagen-based therapies can help anyone seeking natural rejuvenation, volume restoration, and skin refinement. Whether you choose a collagen injection like Linerase or Deusaderm, or opt for a long-lasting biostimulator such as PCL or PDLLA, the key lies in personalised treatment planning. Each modality serves a different purpose: collagen injections are ideal for delicate, superficial applications, while biostimulators are ideal for deep lifting and long-term collagen regeneration.

At Ozhean Zoey Clinic, we pride ourselves on our commitment to collagen science. Our doctors carefully assess your skin condition, age, and aesthetic goals to craft a tailored treatment plan that combines collagen injections, biostimulators, and adjunct therapies. If you're considering collagen therapy in Singapore, book a consultation with us to discover what approach will bring out your skin’s potential.